研究業績リスト
原著論文（査読あり）*はcorresponding
author
生命の起源関連
1. Koichi Nagafuchi, Atsushi Nagira, Hidenori Akiyama, Mitsuru Sasaki1*, Kunio Kawamura, Oligopeptide production from alanine monomer by pulsed corona discharge plasma in ambient and supercritical argon, Chemical Engineering and Science, 1 (3), 41-45, 2013.
2. Nizar El-Murr, Marie-Christine Maurel, Martina Rihova, Jacques Vergne, Guy Hervé, Mikio Kato, Kunio Kawamura*, Behavior of a hammerhead ribozyme in aqueous solution at medium to high temperatures, Naturwissenschaften, 99, 731–738, 2012.
3. Kunio Kawamura*, Takayuki Nakai, Keisuke Ikoma, Hideaki Hisamoto, High-throughput Ru(III) analysis using the hydrothermal flow reactor-mediated FIA by the extreme acceleration of Ru(III) complexation with 1,10-phenanthroline, Talanta, 99, 415–419, 2012.
4.
Yuji Fujii, Terence G. Henares, Kunio Kawamura, Tatsuro
Endo, Hideaki Hisamoto, Bulk- and surface-modified combinable PDMS capillary sensor array as
easy-to-use sensing device with enhanced sensitivity to elevated concentrations
of multiple serum sample components, Lab Chip 12 (8), 1522-1526, 2012.
5.
Erina Tsutsumi,
Terence G. Henares, Shun-ichi Funano,
Kunio Kawamura, Tatsuro
Endo, Hideaki Hisamoto, Single-step sandwich immunoreaction in a square glass capillary
immobilizing capture and enzyme-linked antibodies for simplified enzyme-linked immunosorbent assay, Anal. Sci. 28, 51-56, 2012.
6.
Yosuke Uchiyama, Fumito Okubo, Kozo Akai, Yuji
Fujii, Terence G. Henares, Kunio
Kawamura, Toshio Yao, Tatsuro Endo, Hideaki Hisamoto, Combinable poly(dimethyl siloxane)
capillary sensor array for single-step and multiple enzyme inhibitor assays, Lab on a Chip, 12 (1), 204-208, 2012.
7. Kunio Kawamura,
Hitoshi Takeya, Takao Kushibe, Yuka Koizumi,
Mineral-enhanced hydrothermal oligopeptide formation
at the second time scale, Astrobiology, 11 (5), 461-469, 2011.
8. Kunio Kawamura*,
Hiroki Nagayoshi, Toshio Yao, In situ analysis of
proteins at high temperatures mediated by capillary-flow hydrothermal UV-Vis
spectrophotometer with a water-soluble chromogenic reagent, Anal. Chim. Acta,
667, 88–95 (2010).
9. Kunio Kawamura*,
Hiroki Nagayoshi, Toshio Yao, Stability of ribonuclease A under hydrothermal conditions in relation to
the origin-of-life hypothesis: Verification with the hydrothermal micro-flow
reactor system, Research on Chemical Intermediates, 35 (8-9), 879–891,
2009.
10. Kunio
Kawamura*, Hitoshi Takeya,
Takao Kushibe, Effect of condensation agents and
minerals for oligopeptide formation under mild and
hydrothermal conditions in related to chemical evolution of proteins, Advances
in Space Research, 44 (2), 267–275, 2009.
11. Kunio
Kawamura*, Jun Maeda, Kinetics
and activation parameter analysis for the prebiotic oligocytidylate
formation on Na+-montmorillonite at 0
– 100 °C, J. Phys. Chem. A, 112 (35), 8015-8023, 2008.
12. Kunio
Kawamura*, Masanori Shimahashi, One-step formation of oligopeptide-like
molecules from Glu and Asp in hydrothermal environments, Naturwissenschaften,
95 (5), 449-454, 2008.
13. Kunio
Kawamura*, Hiroki Nagayoshi,
Behavior of DNA under hydrothermal conditions with MgCl2 additive
using an in situ UV-visible spectrophotometer, Thermochimica
Acta, 466, 63-68, 2007.
14. Kunio
Kawamura*, Jun Maeda, Kinetic
analysis of oligo(C) formation from the 5'-monophosphorimidazolide of cytidine with Pb(II) ion catalyst at 10 – 75 oC, Origins Life Evol.
Biospheres, 37 (2), 153-165, 2007.
15. 川村邦男*，中村光，熱力学的な開放系の化学進化実験系の試作とその解析：（１）オリゴグアニル酸の鋳型指示生成反応を用いるモノマーの逐次供給の影響， Viva Origino, 35 (1),
45-51, 2007.
16. Kunio
Kawamura*, Civilization as a biosystem examined by the comparative analysis of biosystems, BioSystems, 90 (1), 139-150, 2007.
17. Kunio
Kawamura*, Minoru Nagahama, Toshio Yao, Inhibitory activity of thermal
copolymers of amino acids for the metal-catalyzed hydrolysis of an RNA
dinucleotide, Advances in Space Research, 38 (6), 1220-1226, 2006.
18. Kunio
Kawamura*, Possible pathways
before and after the RNA world on the basis of experimental and theoretical
evidences, Viva Origino, 33 (4), 258-258, 2005.
19. Kunio
Kawamura*, A new probe for the
indirect measurement of the conformation and interaction of biopolymers at
extremely high temperatures using a capillary flow hydrothermal reactor system
for UV-visible spectrophotometry, Anal. Chim. Acta, 543 (1-2), 236-241, 2005.
20. Kunio
Kawamura*, Minoru Nagahama, Kazuhiro Kuranoue,
Chemical evolution of RNA under hydrothermal conditions and the role of thermal
copolymers of amino acids for the prebiotic degradation and formation of RNA,
Advances in Space Research, 35 (9), 1626-1633, 2005.
21. Kunio
Kawamura*, Teruyuki Nishi, Tomofumi Sakiyama, Consecutive elongation of alanine oligopeptides at the second time range under hydrothermal
condition using a micro flow reactor system, J. Am. Chem. Soc., 127 (2),
522-523, 2005.
22. Kunio
Kawamura*, Behavior of RNA
under hydrothermal conditions and the origins of life, International Journal of
Astrobiology, 3 (4), 301-309, 2004.
23. Kunio
Kawamura*, Kazuhiro Kuranoue, Minoru Nagahama, Prebiotic
inhibitory activity of protein-like molecules to the template-directed
formation of oligoguanylate from guanosine
5’-monophosphate 2-methylimidazolide on a polycytidylic
acid template, Bull. Chem. Soc. Jpn., 77 (7),
1367-1375, 2004.
24. 川村邦男*，岡本文敬，奥田宜子，水溶性カルボジイミドを用いるオリゴヌクレオチドの縮合反応に対する鋳型オリゴヌクレオチドの影響：高温下で働くことをめざしたRNA生成モデルの探索, Viva Origino, 32
(2), 68-80, 2004.
25. Kunio
Kawamura*, Noriyuki Nakahara,
Fumitaka Okamoto, Noriko Okuda, Temperature dependence of the cyclization of
guanine and cytosine mix hexanucleotides with
water-soluble carbodiimide at 0 -75 oC, Viva Origino, 31 (4),
221-232, 2003.
26. Kunio
Kawamura*, Kazuhiro Kuranoue, Influence of 20 common amino acids on the
template-directed formation of oligoguanylate from guanosine 5’-monophosphate 2-methylimidazolide on a polycytidylic acid template, Viva Origino,
31 (3), 188-200, 2003.
27. Kunio
Kawamura*, In situ UV-VIS
detection of the association of water-soluble anionic porphyrin and aromatic
bases in aqueous solution at high temperatures using a capillary flow
hydrothermal reactor system, Anal. Sci., 19 (8), 1199-1202, 2003.
28. Kunio
Kawamura*, Kinetics and
activation parameter analyses of hydrolysis and interconversion
of 2',5'- and 3',5'-linked dinucleoside monophosphate
at extremely high temperatures, Biochim. Biophys. Acta, 1620 (1-3), 199-210, 2003.
29. Kunio
Kawamura*, Kinetic analysis of
cleavage of ribose phosphodiester bond within guanine
and cytosine rich oligonucleotides and dinucleotides
at 65 - 200 oC and its implications on the
chemical evolution of RNA, Bull. Chem. Soc. Jpn., 76
(1), 153-162, 2003.
30. Kunio
Kawamura*, Kazuhiro Kuranoue, Masatosi Umehara,
Chemical evolution of RNA and RNA polymerases: Implications from search for the
prebiotic pathway of formation of RNA from adenosine 5’-triphosphate in the
presence of thermal condensation products of amino acids as primitive enzymes,
Viva Origino, 30 (3), 123-134, 2002.
31. Kunio
Kawamura, In situ UV-VIS
detection of hydrothermal reactions using fused-silica capillary tubing within
0.08 - 3.2 s at high temperatures, Anal. Sci., 18 (5), 715-716, 2002.
32. Kunio
Kawamura*, Fumitaka Okamoto,
Cyclization and dimerization of hexanucleotides
containing guanine and cytosine with water-soluble carbodiimide,
Viva Origino, 29 (4), 162-167, 2001.
33. Kunio Kawamura*, Hydrolytic stability of ribose phosphodiester bonds within several oligonucleotides at
high temperatures using a real-time monitoring method for hydrothermal
reactions, Chem. Lett., 1120-1121, 2001.
34. Kunio
Kawamura*, Kazuhiro Kuranoue, Hisitidine and thermal
copolymers of amino acids containing histidine as
prebiotic inhibitor for the template-directed formation of oligoguanylate
on a poly(C) template, Chem. Lett., 1071-1072, 2001.
35. Kunio
Kawamura*, Masaru Yukioka, Kinetics of the racemization of amino acids at 225
- 275 oC using a real-time monitoring
method of hydrothermal reactions, Thermochimica Acta,
375 (1-2), 9-16, 2001.
36. Kunio
Kawamura*, Masatosi
Umehara, Kinetic analysis of the temperature
dependence of the template-directed formation of oligoguanylate
from the 5'-phosphorimidazolide of guanosine on a
poly(C) template with Zn2+, Bull. Chem. Soc. Jpn.,
74 (5), 927-935, 2001.
37. 川村邦男*，ＲＮＡワールド仮説を生命の熱水起原説から検証する：生命の起原のシナリオの再構築－，Viva Origino, 28 (3),
129-138, 2000.
38. Kunio
Kawamura*，Monitoring hydrothermal reactions on the millisecond time
scale using a micro-tube flow reactor and kinetics of ATP hydrolysis for the
RNA world hypothesis，Bull. Chem. Soc. Jpn., 73 (8),
1805-1811, 2000.
39. Kunio
Kawamura, J. P. Ferris*, Clay
catalysis of oligonucleotide formation: Kinetics of the reaction of the
5'-phosphorimidazolides of nucleotides with the non-basic heterocycles
uracil and hypoxanthine, Origins Life Evol.
Biosphere, 29 (6), 563-591, 1999.
40. Kunio
Kawamura*, Monitoring of
hydrothermal reactions in 3 ms using fused-silica capillary tubing, Chem.
Lett., 1999 (2), 125-126.
41. Kunio
Kawamura*, Naoko Kameyama, Osamu Matumoto,
Kinetics of hydrolysis of ribonucleotide polymers in
aqueous solution at elevated temperatures: implications of chemical evolution
of RNA and primitive ribonuclease, Viva Origino, 27 (2), 107-118, 1999.
42. 川村邦男*，流通式反応器を用いる水熱反応の速度論的解析－398-573Kにおけるアデノシン5'-三リン酸の加水分解反応－，日本化学会誌，1998 (4), 255-262.
43. Kunio
Kawamura*, Capillary
electrophoretic separation of mono and dinucleotides
of adenosine using cyclodextrin solutions with MgCl2
additive, J. Chromatograpy A, 802 (1), 167-177, 1998.
44. 川村邦男*，吉田晶子，松本修，高温水溶液中におけるアデノシン5'-三リン酸の加水分解反応の速度論的研究：ＲＮＡの化学進化における考察， Viva Origino, 25 (3),
177-197, 1997.
45. Ping Z. Ding, Kunio
Kawamura, James. P. Ferris*, Oligomerization of uridine phosphorimidazolides on montmorillonite: A model for the prebiotic synthesis of RNA
on minerals, Origins Life Evol. Biosphere, 26 (2),
151-171, 1996.
46. Kunio
Kawamura, James P. Ferris*,
Kinetics and mechanistic analysis of dinucleotide and oligonucleotide formation
from the 5'-phosphorimidazolide of adenosine on Na+-montmorillonite, J. Am. Chem. Soc., 116 (17), 7564-7572,
1994.
分析化学・環境化学関連
47. Kunio Kawamura,*
Takayuki Nakai, Keisuke Ikoma,
Hideaki Hisamoto, High-throughput Ru(III)
analysis using the hydrothermal flow reactor-mediated FIA by the extreme
acceleration of Ru(III) complexation
with 1,10-phenanthroline, Talanta, accepted 2012.
48. Yuji Fujii, Terence G.
Henares, Kunio Kawamura, Tatsuro
Endo, Hideaki Hisamoto, Bulk- and surface-modified combinable PDMS capillary sensor array as
easy-to-use sensing device with enhanced sensitivity to elevated concentrations
of multiple serum sample components, Lab Chip 2012 accepted.
49. Erina Tsutsumi, Terence G.
Henares, Shun-ichi Funano, Kunio Kawamura, Tatsuro
Endo, Hideaki Hisamoto, Single-step sandwich immunoreaction in a square glass capillary
immobilizing capture and enzyme-linked antibodies for simplified enzyme-linked immunosorbent assay, Anal. Sci. 28, 51-56, 2012.
50. Yosuke Uchiyama, Fumito
Okubo, Kozo Akai, Yuji Fujii, Terence G. Henares, Kunio Kawamura, Toshio Yao, Tatsuro
Endo, Hideaki Hisamoto, Combinable poly(dimethyl siloxane) capillary sensor array for single-step and
multiple enzyme inhibitor assays, Lab on a Chip, 12 (1), 204-208, 2012.
51. Kunio Kawamura,
Keisuke Ikoma, Shukuro
Igarashi, Hideaki Hisamoto, Toshio Yao, Flow
injection analysis combined with a hydrothermal flow reactor: application to
kinetic determination of trace amounts of iridium using a water-soluble porphyrin, Talanta, 84 (5),
1318-1322, 2011.
52. Kunio Kawamura, Shukuro
Igarashi, Takao Yotsuyanagi, Catalytic activity of
noble metal ions for the degradation of 5,10,15,20-tetrakis(4-sulfonatophenyl)porphine in the presence of oxidizing agent and its
application to determination of ultra trace amounts of ruthenium, Microchimica Acta, 172 (3-4),
319-326, 2011.
53. Masaki Kataoka, Hiroki
Yokoyama, Terence G. Henares, Kunio Kawamura, Toshio
Yao, and Hideaki Hisamoto, Reagent-release capillary array-isoelectric focusing
device as a rapid screening device for IEF condition optimization, Lab Chip.
10, 3341-3347, 2010.
54. Terence G. Henares, Erina
Tsutsumi, Hiromi Yoshimura, Kunio Kawamura, Toshio Yao, Hideaki Hisamoto*, Single-step ELISA
capillary sensor based on surface-bonded glucose oxidase, antibody, and
physically-adsorbed PEG membrane containing peroxidase-labeled antibody, Sens.
Actuators B. 149, 319–324 (2010).
55. Erina Tsutsumi, Terence G.
Henares, Kunio Kawamura, Toshio Yao,
Hideaki Hisamoto, Facile preparation method of a disposable capillary biosensor
using an ion-selective optode membrane and a
dissolvable enzyme membrane and its application to urea sensing, Chem. Lett., 39(5), 436-438, 2010.
56. Kunio Kawamura*,
Kazumichi Shibuya, Akitsugu Okuwaki,
Morphology of aluminum phosphate by the Al-EDTA mediated particle formation in
aqueous solutions at high temperatures, Materials Research Bulletin, 42 (2), 256-264,
2007.
57. Kunio Kawamura*,
Shukuro Igarashi, Takao Yotsuyanagi, Kinetics of the accelerator ligand effect for
the complex formation of Cd(II) ion with a cationic water-soluble porphyrin, Inorganica Chimica Acta, 360
(10), 3287-3295, 2007.
58. Kunio
Kawamura*, Shukuro Igarashi,
Takao Yotsuyanagi, Stopped-flow spectrophotometric determination of nM level of
Pb(II) using 5,10,15,20-terakis(1-methylpyridinium-4-yl)porphine, Microchimica Acta, 157 (1-2), 87-91, 2007.
59. Kunio
Kawamura*, Shukuro Igarashi,
Takao Yotsuyanagi, Acceleration effect of ethanol for the complexation of
rhodium(III) with a cationic water-soluble porphyrin and an attempt to develop
a determination method of rhodium(III), Can. J. Anal. Sci. Spec., 51 (4),
201-206, 2006.
60. Kunio Kawamura*, Shukuro Igarashi, Takao Yotsuyanagi, Acceleration
of metal ion incorporation into cationic porphyrin by 5-sulfo-8-quinolinol and
spectrophotometric determination of nickel(II), Microchimica
Acta, 153 (3-4), 145-150, 2006.
61. Kunio Kawamura*,
Keiji Takahashi, Akitsugu Okuwaki, Influence of pH and diluent for the ion-pair
solvent extraction of aromatic carboxylic acids using quaternary ammonium salts,
Separation Science and Technology, 41 (12), 2795-2806, 2006.
62. Kunio
Kawamura*, Akitsugu
Okuwaki, T. V. Verheyen, G.
J. Perry, Separation of aromatic carboxylic acids using quaternary ammonium
salts on reversed-phase HPLC 2. Application for the analysis of Loy Yang coal
oxidation products, Separation Science and Technology, 41 (4), 723-732, 2006.
63. Kunio
Kawamura*, Akitsugu
Okuwaki, T. V. Verheyen, G.
J. Perry, Separation of aromatic carboxylic acids using quaternary ammonium
salts on reversed-phase HPLC 1. Separation behavior of aromatic carboxylic
acids, Separation Science and Technology, 41 (2), 379-390, 2006.
64. Kunio
Kawamura*, Hideki Nagano, and Akitsugu Okuwaki, Extraction of
benzene and naphthalene carboxylic acids using quaternary ammonium salts as a
model study for the separation of coal oxidation products, Separation Science
and Technology, 40 (13), 2761-2771, 2005.
65. Y. Fujishiro, H. Yabauki, K. Kawamura,
T. Sato*, A. Okuwaki, Preparation of needle-like
hydroxyapatite by homogeneous preparation under hydrothermal conditions, J.
Chem. Tec. Biotec., 57, 349-353, 1993.
66. 吉岡敏明，安田真也，川村邦男，佐藤次雄，奥脇昭嗣*，高温アルカリ水溶液中におけるポリ塩化ビニル粉末の酸素酸化，日本化学会誌，1992 (5), 534-541.
67. Kunio Kawamura*,
Shukuro Igarashi, Takao Yotsuyanagi, Acceleration effect of L-tryptophan on
metal ion exchange reaction of cadmium(II) with watersoluble-porphyrin-lead(II) complex and its application to
stopped-flow spectrophotpmetryic determination of nM
level of cadmium(II), Anal. Sci., 4 (2), 175-179, 1988.
68. Kunio
Kawamura*, Shukuro Igarashi,
Takao Yotsuyanagi, Porphyrin as reagent of new indicator reaction for the
catalytic determination of ultra trace amounts of ruthenium(III), Chem. Lett.,
2217-2220, 1987.
69. Kunio
Kawamura*, Hiroshi Kasahara, Shukuro Igarashi, Takao Yotsuyanagi, Kinetics of
pyridine derivatives as accelerators for the incorporation reaction of
cadmium(II) into porphyrin and association behaviors of the accelerators with
porphyrin, Chem. Lett., 2365-2368, 1987.
著書（査読あり）
1.
Kunio
Kawamura, “Reality of the emergence of
life-like systems from simple prebiotic polymers on primitive earth” in
“GENESIS - IN THE BEGINNING:
Precursors of Life, Chemical Models and Early biological Evolution” Eds. by Joseph Seckbach and Richard Gordon, Springer,
pp123-144, 2012.
2. Kunio Kawamura, Chapters “Activated Nucleotide”,
“Nucleotide Phosphirimidazolide”, and “Oligonuleotide”, in “Encyclopedia of Astrobiology”, Eds. by
Ricardo Amils, Muriel Gargaud,
Jose Cernicharo Quintanilla, Henderson James Cleaves,
William M. Irvine, Daniele Pinti, Michel Viso, 1853p, Springer, 2011.
3. Kunio Kawamura*,
“The relative importance of genes, subjectivity, and self-organization for the
origin and evolution of life”, in “In the shadow of Darwinism: Alternative
evolutionary theories in the 20th century”, Eds. by G. S. Levit,
I. Y. Popov, U. Hossfeld, O. Breidbach
pp. 218-239, Fineday-press, St-Petersburg, 2003.（ロシア語）
4. Kunio
Kawamura*, “The Origin of Life
from the Life of Subjectivity”, in "Fundamentals of Life", Eds. by G.
Palyi, C. Zucchi, L. Caglioti, pp. 563-574, Elsevier, Paris, 2002.
5. Kunio
Kawamura*, "Capillary
Electrophoresis of Nucleic Acids" in “Encyclopedia of Analytical Chemistry”,
Ed. by R. A. Meyers, Volume 6, pp. 4871 – 4893, John Wiley & Sons
Ltd, Chichester, UK, 2000.
総説・解説（査読あり）
1. Kunio Kawamura,
Drawbacks of the ancient RNA-based life-like system under primitive earth
conditions, Biochimie,
94, 1441-1450, 2012.
2. Kunio Kawamura,
Development of micro-flow hydrothermal monitoring systems and their
applications to the origin of life study on earth, Anal. Sci., 27, 675-683, 2011.（7月）
3. 川村邦男，生命起源の解明をめざした熱水フローリアクターシステムの開発，ぶんせき，2011 (2) 104-107.
4. 川村邦男，熱水フローリアクターの技術開発と化学進化研究への適用：生命的システムの実験的検証のための第２段階，Viva Origino,
38, 40-45, 2010.
5. 川村邦男，前生物的化学に基づいてRNAワールド仮説を検証する，Viva Origino, 37 (3), 31-42, 2009.
6. 川村邦男，地球内外の生命探査のための分析技術，ぶんせき，2007(10)，545-546．
7. 川村邦男，分子進化工学によって創製されるアプタマーを用いたセンサー,ぶんせき,
2006(1), 35-35.
8. 川村邦男，生命の主体性に基づく生命系の時間発展の理論 －化学進化，生物進化，文化・文明の発展を生命現象としてみる－，A unified theory for the description of biosystems
based on the subjectivity of life: chemical evolution, biological evolution,
culture and civilization, Viva Origino, 33 (1), 17-35, 2005.
9. 川村邦男，生命の起源を核酸化学から探る－最初の遺伝子はどのように生まれたか，化学と教育，vol. 48, 232-235,
2000.
10. 川村邦男，ＲＮＡの人工分子進化法，ぶんせき，1997 (6), 481-483.
国際会議・国内会議論文（査読あり）
1. Kunio Kawamura, Recent progress
for the peptide synthesis using hydrothermal-microflow
reactor systems, Peptide Science, 123-124, 2012.
2. Combinable PDMS capillary
sensor array for multiple chemical sensing: Sensitivity enhancement and
facilitation of sample introduction based on surface modification of PDMS, Yuji Fujii, Terence.
G. Henares, Kunio Kawamura, Tatsuro
Endo, Hideaki Hisamoto, Proc. MicroTAS,
1152-1154, 2011.
3. Simple and
highly-sensitive enzyme activity assay based on reagent-release capillary -
isoelectric focusing (RRC-IEF) towards the development of multi analyte sensing micro device capable of detecting both
proteins and enzyme activities, Yuto Nogawa, Hiroki Yokoyama, Kunio Kawamura, Tatsuro
Endo, Hideaki Hisamoto, Proc. MicroTAS,
2025-2027, 2011.
4. Kunio Kawamura*,
Temperature limit for the emergence of life-like system deduced from the
prebiotic chemical kinetics under the hydrothermal conditions, Proceedings of
the Twelfth International Conference on the Simulation and Synthesis of Living
Systems, Odense, Denmark, Edited by, H. Fellermann,
M. Dörr, M. M. Hanczyc,
L. L. Lauren, S. Maurer, D. Merkle, P.-A. Monnard, K. Støy, S.
Rasmussen, 37-44, 2010.
5. Kunio
Kawamura*, Teruyuki
Nishi, Tomofumi Sakiyama,
Toshio Yao, Behavior of alanine oligopeptides in
aqueous solution at extremely high temperatures, Proceedings of The 42nd
Japanese Peptide Symposium, 115-116, 2006.
6. Kunio
Kawamura*, Is the RNA world hypothesis
consistent with the hydrothermal origin of life? Geochimca
et Cosmochimca Acta, Suppl., pp.A208, 2003.
7. Minoru Nagahama, Kunio Kawamura*, A new approach for the
cooperative chemical evolution of nucleic acids and proteins under the
primitive earth environment, Nucleic Acids Res. Suppl., No. 2, 279-280, 2002.
8. Kunio
Kawamura*, Comparison of the
rates of prebiotic formation and hydrolysis of RNA under hydrothermal
environments and its implications on the chemical evolution of RNA, Nucleic
Acids Res. Suppl. 1, 239-240, 2001.
9. Kunio
Kawamura*, Fumitaka Okamoto,
Condensation reaction of hexanucleotides containing
guanine and cytosine with water soluble carbodiimide,
Nucleic Acids Res. Suppl., 44, 217-218, 2000.
10. Kunio
Kawamura*, Measurement of the
rate of RNA hydrolysis in aqueous solution at elevated temperatures using a new
monitoring method for hydrothermal reactions, Nucleic Acids Res. Symp. Ser., 42, 289-290, 1999.
報告書・その他（査読なしまたは簡単な査読のみ）
1. 川村邦男，高温高圧水反応用の高性能グリーン固体触媒の開発ツール（Research tool for the development of high-performance solid-state green catalysts under hydrothermal conditions），マツダ財団研究報告書（ISSN 1344-0497），Vol. 24, pp. 11-18, 2012.
2. 川村邦男，生命の起源雑感－酵素の起源について，Viva Origino, 33 (3), 236-237, 2005.
3. 澤井宏明，川村邦男，解説「シンポジウム４」From Molecules to Life-Like Systems & RNA
World,“分子から生命システムへ”および“RNAワールド”, Viva Origino, 33 (3), 216-220, 2005.
4. 川村邦男，高温水溶液反応の新しい高速追跡法を用いるin situ紫外可視吸光分析（In situ UV-VIS absorption spectrophotometry
using a new monitoring method for reactions in aqueous solutions at high
temperatures），マツダ財団研究報告書（ISSN 1344-0497），Vol. 16, pp. 33-39, 2004.
5. 川村邦男，22世紀につながる学問と技術をつくる，稲盛財団スカラーズソサイエティ会報，2002年9月．
会議報告等（査読あり）
1.
Kunio Kawamura*, Hitoshi Takeya, Ai Akiyoshi,
Masanori Shimahashi, Oligopeptide
formation under hydrothermal conditions using a micro-flow hydrothermal
reactor, Origins Life Evol. Biospheres, 39, 202-203,
2009.
2.
Kunio Kawamura*, Jun Maeda, Hiroki Nagayoshi, An
RNA world under hydrothermal environments on the basis of kinetic analyses of
the prebiotic formation of RNA, Origins Life Evol.
Biospheres, 39, 203-204, 2009.
3.
Chika Kaede, Kunio Kawamura*,
Hydrolysis of 3',5'- and 2',5'-linked dinucleotide monophosphate in aqueous
solution at 175 - 240 oC, Origins Life Evol. Biosphere, 30, 281, 2000.
4.
Kunio Kawamura*, Chemical evolution of RNA in aqueous solution at high
temperatures : a new method for monitoring of hydrothermal reactions, Origins
Life Evol. Biosphere, 30(2-4), 282, 2000.
5.
Kunio Kawamura*, James P. Ferris, Kinetics and mechanistic investigations
for oligonucleotide formation from 5'-phosphorimidazolide of adenosine, uridine and inosine on Na+-montmorillonite, Origins Life Evol.
Biosphere, 26 (2), 392-393, 1996.
6.
Kunio Kawamura, James P. Ferris*, Kinetics of dimerization and oligomerization of the 5'-phosphorimidazolide of adenosine
on Na+-montmorillonite, Origins Life Evol. Biosphere, 24(2-4), 226-227, 1994.
7.
J. P. Ferris*,
Z. P. DING, K. Kawamura, K. J.Prabahar, Oligomerization of
5'-activated nucleotides on montmorillonite clay - a
model for the prebiotic synthesis of RNA, Abstracts of papers of the American
Chemical Society 207: 28-GEOC Part 1, MAR 13 1994.
国際学会講演（基調・招待・依頼講演を含む）（*は複数の場合の登壇者）
1. K. Kawamura*, Behaviors
of RNA and peptides under the hydrothermal environments towards the ancient
life-like system, the Symposium "The Future of RNA Worlds", Acides Nucléiques et BioPhotoNique - UPMC 4 Place Jussieu
Paris UPMC, February 24, 2012. (Invited)
2. K. Kawamura*, Behaviors
of RNA and peptides under the hydrothermal environments towards the ancient
life-like system, Invited Seminar, University de Strasbourg and JSPS Strasbourg
office, February 17, 2012. (Invited)
3. K. Kawamura*, Evaluation of the RNA world hypothesis and the
GADV hypothesis on the basis of the hydrothermal origin-of-life hypothesis, Narasaho-Seminar on the Origin of Life, January 17, 2011,
Nara. (Invited)
4. K. Kawamura*, Development of real-time and in situ UV-visible
monitoring methods for hydrothermal reactions and its applications to the
origin of life study, Pachifichem 2010, The 2010
International Chemical Congress of Pacific Basin Societies, December 15 –
20, 2010, Honolulu, Hawai.
5. Kunio. Kawamura*,
Keisuke Ikoma, Tomoko Yasuda, Hiroki Nagayoshi, Hitoshi Takeya, Shukuro
Igarashi, Hideaki Hisamoto, Toshio Yao, Development
of micro-flow analytical techniques for hydrothermal reactions, Pachifichem 2010, The 2010 International Chemical Congress
of Pacific Basin Societies, December 15 – 20, 2010, Honolulu, Hawai.
6. K. Kawamura*, Temperature limit for the emergence of
life-like system deduced from the prebiotic chemical kinetics under the
hydrothermal conditions, Artificial Life 12, Odense, Denmark, 19-23, August,
2010.
7. K. Kawamura*, Chemical evolution of life-like system under
hydrothermal environments: prebiotic formation, degradation, and functions
regarding protein-like molecules and RNA, “COSPAR Scientific Assembly 2010”, Bremen,
Germany, 18-24 July 2010.
8. K. Kawamura*, K. Ikoma, S. Igarashi, H. Hisamoto, T. Yao,
Hydrothermal reactor system for the flow injection analysis of trace metal
ions, 16th International conference on flow injection analysis, Pataya, Thailand, April 26-30, 2010.
9. K. Kawamura*, H. Takeya, T. Kushibe,
Investigations of mineral activity for the biopolymer formation under
hydrothermal conditions using a mineral-mediated micro-flow reactor, Gordon
Research Conference: Origin of Life, Galveston, USA, January, 10-15, 2010.
10. K. Kawamura*, H. Takeya, A. Akiyoshi,
M. Shimahashi, Oligopeptide
formation under hydrothermal conditions using a micro-flow hydrothermal
reactor, in “15th International Conference on the Origin of Life”, “12th ISSOL
meeting”, Florence, Italy, August 24-29, 2008.
11. K. Kawamura*, J. Maeda, H. Nagayoshi, An RNA world under
hydrothermal environments on the basis of kinetic analyses of the prebiotic
formation of RNA, in “15th International Conference on the Origin of Life”,
“12th ISSOL meeting”, Florence, Italy, August 24-29, 2008.
12. K. Kawamura*, T. Nishi, M. Shimahashi,
T. Sakiyama, H., Takeya, A. Akiyoshi,
Search for the effective and higher oligopeptide
formation under hydrothermal conditions using a micro-flow hydrothermal reactor
system, in “International Workshop on Chemical Evolution & Origin of Life”,
Department of Chemistry, Indian Institute of Technology Roorkee,
Roorkee, India, March 14-16, 2008, (招待講演).
13. K. Kawamura, Possible pathways before and after the RNA
world on the basis of experimental and theoretical evidences, in “International
Symposium on Origins of Life and Astrobiology (ISOLAB’05)”, Niigata, June 27 –
July 2, 2005.
14. K. Kawamura, J. Maeda*, T. Yao, Kinetics and temperature
dependence of the oligocytidylate formation from 5’-phosphorimidazolide
of cytidine with Pb2+ ion, in “International
Symposium on Origins of Life and Astrobiology (ISOLAB’05)”, Niigata, June 27 –
July 2, 2005.
15. T. Yao*, T. Teratani, K. Kawamura, Amperometric
determination of formaldehyde and phenol in rainwater and automobile exhaust
gas by a flow-injection biosensor system with an on-line microdialysis
sampling, in “International Conference on Flow Injection Analysis”, Las Vegas,
USA, April, 2005.
16. Kunio
Kawamura, Chemical evolution of
RNA under hydrothermal conditions and the role of thermal copolymers of amino
acids for the prebiotic degradation and formation of RNA, “COSPAR Scientific
Assembly 2004”, Paris, France, 18-25 July 2004, (招待講演).
17. Kunio
Kawamura, A new non-darwinian evolutionary theory developed in the far east and
the origin of biosystems, in “Alternative
Evolutionary Theories in the 20th and 21st Centuries in the International and
Interdisciplinary Perspective”, St.Petersburg,
Russia, 3-5 June, 2004, (依頼講演).
18. Kunio
Kawamura, Is the RNA world
hypothesis consistent with the hydrothermal origin of life? in “13th V. M.
Goldschmidt Conference”, Kurashiki, Japan, September 7-12, 2003, (招待講演).
19. Kunio
Kawamura, Stability of RNA and
origins of life under hydrothermal environments: an experimental approach for
monitoring of RNA hydrolysis at high, in “The International Chemical Congress
of Pacific Basin Society”, Honolulu, Hawaii, USA, December 14 - 19, 2000, (招待講演).
20. Kunio
Kawamura, The origin of life
from the life of subjectivity, in “Workshop on Life”, Modena, Italy, September
3 - 8, 2000, (基調講演，招待講演).
21. Chika Kaede*, Kunio Kawamura, Hydrolysis of 3',5'- and
2',5'-linked dinucleotide monophosphate in aqueous solution at 175 - 240 oC, in “12th International Conference on the
Origin of Life”, San Diego, USA, July 11-16, 1999.
22. Kunio Kawamura Chemical evolution of RNA in aqueous solution
at high temperatures: A new method for monitoring of hydrothermal reactions, in
“12th International Conference on the Origin of Life”, San Diego, USA, July 11-16, 1999.
23. Kunio
Kawamura, Kinetic analysis of
hydrothermal reactions: Monitoring of ATP hydrolyssis
by flow tube reactor, in “Kyoto University International Conference on
"The role of radiation in the origin and evolution of life"”, Izumiohtsu, March 2-5, 1998.
24. Kunio
Kawamura, N. Kameyama, O. Matumoto, Hydrolysis
of polyribonucleotides in aqueous solution at
elevated temperatures, in “Kyoto University International Conference on
"The role of radiation in the origin and evolution of life"”, Izumiohtsu, March 2-5, 1998.
25. M. Umehara*, K.
Kawamura, Kinetic analysis of the poly(C) template-directed synthesis of oligoguanylates in aqueous solution at elevated
temperatures, in “Kyoto University International Conference on "The role
of radiation in the origin and evolution of life"”, Izumiohtsu,
March 2-5, 1998.
26. Kunio
Kawamura, Capillary
electrophoretic separation of mono and dinucleotides
of adenosine using cyclodextrin solutions with
magnesium chloride additive, in “10th International Symposium on High
Performance Capillary Electrophoresis”, Kyoto, 8-11 July 1997..
27. Kunio
Kawamura*, James P. Ferris,
Kinetics and mechanistic investigations for oligonucleotide formation from
5'-phosphorimidazolide of adenosine, uridine and inosine on Na+-montmorillonite,
in “11th International Conference on the Origin of Life”, Orleans, France, July
7-12, 1996.
28. Kunio
Kawamura*, James P. Ferris,
Kinetics and mechanistic investigations for oligonucleotide formation from
5'-phosphorimidazolide of adenosine, uridine, and inosine on Na+-montmorillonite,
in “Gordon conference”, Ventura, California, USA, January 7–12, 1996.
29. J. P. Ferris*, Ping Z. Ding, K. Kawamura, J. K. Prabahara,
Oligomerization of 5'-activated nucleotides on montmorillonite clay – A model for the prebiotic
synthesis of RNA, in “Annual meeting of Americal
Chemical Society”, Mar. 13, 1994.
30. Kunio
Kawamura*, James P. Ferris,
Kinetics of dimerization and oligomerization of the
5'-phosphorimidazolide of adenosine on Na+-montmorillonite,
in 10th the International conference on the origin of life, 7th ISSOL meeting,
July 4-9, 1993, Barcelona, Spain.
31. Kunio
Kawamura*, James P. Ferris,
Kinetics and mechanistic investigations for dinucleotide and oligonucleotide
formation from 5'-phosphorimidazolide of adenosine and uridine
on Na+-montmorillonite, in “Gordon
conference”, Salve Regina University, Newport, Rhode Island, August 21 –
26, 1994.
31.
国内学会等の招待講演・依頼講演（*は複数の場合の登壇者）
1.
川村邦男，「熱水分析技術の開発と化学進化研究への展開，生命の起原および進化学会第３５回学術講演会，2010年3月15-17日（函館），（依頼シンポジウム講演）
2.
川村邦男，「タンパク質の化学進化と生命の熱水起原，国際高等研究所フェロー（池原）研究会 「生命の本質－遺伝子、遺伝暗号、タンパク質および生命の起源」，平成21年12月11－ 12日（木津川市），（招待講演）
3.
川村邦男，「生命の定義と化学進化研究に基づいてリアルな原始生命体を描く，国際高等研究所フェロー（池原）研究会 「生命の本質－遺伝子、遺伝暗号、タンパク質および生命の起源」，平成22年2月26-27日（木津川市），（招待講演）
4.
川村邦男，「生命らしさからみるRNAワールド，国際高等研究所フェロー（池原）研究会 「生命の本質－遺伝子、遺伝暗号、タンパク質および生命の起源」，平成21年9月25-26日（木津川市），川村邦男（招待講演）
5. 川村邦男，「前生物的化学に基づいてRNAワールド仮説を検証する」，生命の起原および進化学会第３４回学術講演会，熊取，2009年3月17-19日，（依頼シンポジウム講演）．
6.
川村邦男，「化学の冒険：生命の起源への挑戦」，第201回自然環境論セミナー，神戸大学，（神戸，2008年12月10日），（招待講演）．
7.
川村邦男，竹家均，嶋橋政徳，秋吉藍，西輝之，崎山智文，「熱水マイクロフローリアクターを用いるオリゴペプチドの非生物的生成反応の速度解析」， 2008年度日本地球化学会年会（東京，2008年9月），（依頼講演）
8. 川村邦男，「RNAワールド仮説を生命の熱水起源から検証する」，生命の起原－夏の学校，奈良女子大学，2006年8月12日，（招待講演）．
9. 川村邦男，「オリゴペプチドの合成方法およびその装置」,近畿バイオ関連産業プロジェクト連携促進事業 技術シーズ公開会（大阪科学技術センター 8F 中ホール，2005年9月5日）（招待講演）．
10. 川村邦男，「原始熱水環境における核酸の化学進化に対する新しい計測化学的アプローチ」，“分離機能とセンシング機能の化学”セミナー，仙台，2004年1月24日，（招待講演）．
11. 川村邦男，「RNAワールド仮説を生命の熱水起原説から検証する」，生命の起原および進化学会第２５回学術講演会，横浜，2000年3月14-16日，（招待講演）．
12.
川村邦男，「RNAの化学進化過程の速度論的研究」，生命の起原－夏の学校，河口湖，1998年7月21-23日，（招待講演）．
13. 川村邦男*，吉田晶子，松本修，梅原雅俊，「高温水溶液中における核酸の分解および生成反応の速度論的研究」,第22回生命の起原および進化学会学術講演会，長岡，1997年3月16-18日，（依頼講演）．
14. 四ッ柳隆夫，川村邦男*，「水溶性ポルフィリンを用いる10-10
MレベルのRu(III)の接触分析法の開発」，第14回ルテニウム研究会（東京，国立教育会館，1987年6月30日），（依頼講演）．
特許：
1. 固体充填フロー型高温高圧液相反応装置およびオリゴペプチドの合成法，出願人：大阪府立大学，発明者：川村邦男，特願2010-21576「H22，2，2」
2. オリゴペプチドの製造方法，出願人：大阪府立大学，発明者：川村邦男，特願2009-248365「H21，10，29」
3. オリゴペプチドの合成方法及びその装置，出願人：大阪府，発明者：川村邦男，特願2004-164287「Ｈ16，6，2」
4. 高温高圧溶液反応の高速紫外可視吸光光度法用反応追跡分析装置，出願人：科学技術振興事業団，発明者：川村邦男，特願2001-293712特開2003-98091「H, 13, 9, 26」
5. 高温高圧溶液反応の高速追跡方法及びそれに用いる装置，出願人：科学技術振興事業団，発明者：川村邦男，特願平11-973，「H, 11, 1, 6」特開2000-199764（日本国特許庁（ＪＰ））７月 (2000)，特許：3378936．
6. ｐＨ感応性固体材料，出願人：東亜電波工業株式会社，発明者：四ッ柳隆夫，星野仁，五十嵐淑郎，川村邦男，勝又禎宏，特開平01-148961．